Research year student for project on disseminated intravascular coagulation, Aarhus University Hospital

Title: The prognostic role of blood type in disseminated intravascular coagulation

Background

Disseminated intravascular coagulation (DIC) is a life-threatening disease entity. It is a complication of severe infection, malignant disorder, serious obstetric conditions, trauma, cardiac arrest, and less common conditions. The condition is known for its poor prognosis and limited treatment options and is characterized by activation of the coagulation system with loss of inhibitory anticoagulant proteins, resulting in widespread clotting in the microvasculature leading to organ failure. Consumption of platelets and endothelial dysfunction may lead to significant bleeding.

We are currently establishing the DANish Disseminated Intravascular Coagulation (DANDIC) cohort, comprising approximately 3500 patients with DIC in the Central Denmark Region from 2011-2021. The dataset will be enriched with detailed clinical data from electronic medical charts on aetiologies, bleeding, microthrombus formation, organ failure, thrombosis, treatments, and comorbidities. The cohort will aim to answer several research questions regarding incidence, prognosis, prognostic factors, and treatment. The research year project will investigate the prognostic role of blood type in patients with DIC using the DANDIC cohort.  

Additional information

We are looking for an ambitious research year student with an interest in register-based research. The project is scheduled to start 1 February 2023 and is fully funded. The applicant is expected to contribute to the application for enrollment at the Aarhus University with deadline in October 2022.

You will be a part of the research group of the Thrombosis and Hemostasis Research Unit. During the project period, you will work closely with PhD student Simon Bertram Flæng, other research year students, and senior researchers. The candidate is also expected to take part in the academic life of the department. We expect at least one publication in an international peer-reviewed journal with you as the first author.

If you are interested in joining our group, please send us your motivation and CV before 1 August 2022.

Supervisors

Kasper Adelborg, Associate Professor, MD, PhD, Department of Clinical Biochemistry, Aarhus University Hospital (co-supervisor)
Simon Bertram Flæng, PhD student, MD, Department of Clinical Biochemistry, Aarhus University Hospital (co-supervisor)

Contact

Simon Bertram Flæng
E-mail: siflae@clin.au.dk       
Phone: +45 42 66 88 70